纤维素纳米纤丝复合材料在药物缓释中的应用

Application of Cellulose Nanofibrils Composite Materials in Drug Release System

关键词:  纤维素  纤维素纳米纤丝  药物缓释

Key Words:cellulose  cellulose nanofibrils  drug release

摘要:纳米纤维素具有可再生、环境友好、可生物降解、比表面积大、弹性模量高、生物相容性好等优异特性。利用纤维素纳米纤丝开发药物载体材料，有助于促进农林生物质资源的高值化应用。本文系统地综述纤维素纳米纤丝复合水凝胶材料、复合气凝胶材料、复合膜材料在药物缓释领域中的研究现状，阐述其药物缓释机理，并展望纳米纤维素在药物缓释领域的发展方向。

Abstract:Nanocellulose has many excellent characteristics such as renewable， environmentally friendly， biodegradable， large specific surface area， high elastic modulus and good biocompatibility. Using nanocellulose to develop drug carrier materials is helpful to promote the high-value application of agricultural and forestry biomass resources. The recent advances of cellulose nanofibrils composite hydrogels， composite aerogels， and composite films in drug release system were reviewed in this paper. The mechanism of drug release was explained in detail. The development trend of nanocellulose in the field of drug release was envisioned.